Meet the
PsoriaSiblings you didn’t know you had

That's right! There are common factors involved in the development of plaque psoriasis (PsO), psoriatic arthritis (PsA), and inflammatory bowel disease (IBD) that could mean they are related.1-3

And, just like siblings, they may show up uninvited—individually or together—and PsA could even bring the risk of permanent joint damage.1,2,4,5

References

  1. Sun Y, Li Y, Zhang J. The causal relationship between psoriasis, psoriatic arthritis, and inflammatory bowel diseases. Sci Rep. 2022;12(1):20526. doi:10.1038/s41598-022-24872-5
  2. Schön MP. Adaptive and innate immunity in psoriasis and other inflammatory disorders. Front Immunol. 2019;10:1764. doi:10.3389/fimmu.2019.01764
  3. Rendon A, Schäkel K. Psoriasis pathogenesis and treatment. Int J Mol Sci. 2019;20(6):1475. doi:10.3390/ijms20061475
  4. Hen O, Di Matteo A, Dubash SR, et al. High prevalence of radiographic erosions in early, untreated PsA: results from the SpARRO cohort. RMD Open. 2024;10(2):e003841. doi:10.1136/rmdopen-2023-003841
  5. Eppinga H, Poortinga S, Thio HB, et al. Prevalence and phenotype of concurrent psoriasis and inflammatory bowel disease. Inflamm Bowel Dis. 2017;23(10):1783–1789. doi:10.1097/MIB.0000000000001169